CS101 Introduction to Computing is the fundamental gateway course for all computing, software engineering, information technology, and science students at the Virtual University of Pakistan. Based on modern VU course handouts and classic foundational references including Computer Science: An Overview by J. Glenn Brookshear, this curriculum introduces learners to the core breadth of computational thinking. The syllabus begins with the history of computing, Boolean operations, logic gates, and low-level bit representation across integer two's complement, floating-point numbers, text encoding (ASCII and Unicode), and multimedia compression. Students study computer hardware architecture, CPU machine cycles, mass storage devices, and operating system mechanisms including process management, multiprogramming, scheduling, deadlocks, and exterior security threats. The course delivers comprehensive modules on networking topologies, client-server models, TCP/IP protocols, and modern web application development utilizing HTML, Dreamweaver, and structured web layouts. Furthermore, learners master algorithmic problem solving through pseudocode, iterative control loops, insertion sort, binary search, and recursive logic, before exploring high-level programming language paradigms, object-oriented software engineering lifecycle models, and relational database systems with SQL and MS Access. Fully aligned with official VU lecture handouts, solved past papers by Moaaz and Waqar Siddhu, and lecture-by-lecture solved practice MCQs, this course provides an indispensable foundation for higher-level programming and computer science degree tracks.